Disease mechanisms in neuropathic itch

  title={Disease mechanisms in neuropathic itch},
  author={Andreas Binder and Jana Koroschetz and Ralf Baron},
  journal={Nature Clinical Practice Neurology},
Itch, also known as pruritus, is an unpleasant cutaneous sensation that provokes the desire to scratch. Itch is a common symptom of inflammatory skin disorders, but it can also occur in neurological diseases associated with injury to nervous tissue, in the absence of any skin disease and without any notable physiological stimuli in the periphery. This 'neuropathic' type of itch occurs either in combination with neuropathic pain or independently and is thought to be underdiagnosed. In this… CONTINUE READING
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