Disease location, anti-Saccharomyces cerevisiae antibody, and NOD2/CARD15 genotype influence the progression of disease behavior in Crohn's disease.

@article{Smith2004DiseaseLA,
  title={Disease location, anti-Saccharomyces cerevisiae antibody, and NOD2/CARD15 genotype influence the progression of disease behavior in Crohn's disease.},
  author={Ben R K Smith and Ian D. R. Arnott and Hazel E. Drummond and Elaine R. Nimmo and Jack Satsangi},
  journal={Inflammatory bowel diseases},
  year={2004},
  volume={10 5},
  pages={
          521-8
        }
}
BACKGROUND Crohn's disease (CD) is characterized by heterogeneity of phenotype. The Vienna classification can be used to classify CD, and recent data illustrate that behavior evolves over the course of the disease. Clinical and biological influences on disease progression remain unclear. We examined the associations of CD disease progression at diagnosis and for up to 20 years of follow-up. METHODS Two hundred thirty-one well-characterized CD patients were studied. Demographic, clinical, and… CONTINUE READING

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