Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder

@inproceedings{Dempster2011DiseaseassociatedEC,
  title={Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder},
  author={Emma L. Dempster and Ruth Pidsley and Leonard C. Schalkwyk and Sheena F Owens and Anna Georgiades and Fergus Kane and Sridevi Kalidindi and Marco M. Picchioni and Eugenia Kravariti and Timothea Toulopoulou and Robin MacGregor Murray and Jonathan Mill},
  booktitle={Human molecular genetics},
  year={2011}
}
Studies of the major psychoses, schizophrenia (SZ) and bipolar disorder (BD), have traditionally focused on genetic and environmental risk factors, although more recent work has highlighted an additional role for epigenetic processes in mediating susceptibility. Since monozygotic (MZ) twins share a common DNA sequence, their study represents an ideal design for investigating the contribution of epigenetic factors to disease etiology. We performed a genome-wide analysis of DNA methylation on… CONTINUE READING
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