Disease Versus Disease: How One Disease May Ameliorate Another

  title={Disease Versus Disease: How One Disease May Ameliorate Another},
  author={E. Richard Stiehm},
  pages={184 - 191}
  • E. R. Stiehm
  • Published 1 January 2006
  • Medicine, Biology
  • Pediatrics
Systemic disease, either genetic or acquired, may prevent or decrease the severity of another disease. These observations have led to important therapeutic advances. The best-known examples are Edward Jenner's use in 1798 of cowpox to prevent smallpox and J.B. Haldane's 1942 observation that erythrocyte disorders such as thalassemia and sickle cell disease modify the severity of malaria. Patients with and carriers of cystic fibrosis may have genetic resistance to tuberculosis and/or secretory… 

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