Discriminative stimulus properties of pizotifen maleate (BC105): a putative serotonin antagonist

Daniel J. Minnema, Jean S. Hendry, John A. Rosecrans
Published 1984 in Psychopharmacology

Abstract

Rats were trained to discriminate the putative serotonin (5-HT) antagonist, pizotifen maleate (BC105), from saline using a two-lever drug discrimination paradigm. Pizotifen maleate (6 mg/kg, 14.6 μmol/kg, IP) or saline was administered 55 min prior to the operant training session. The pizotifen discriminative stimulus (DS) had a rapid onset (less than 7 min… (More)

DOI: 10.1007/BF00429735

4 Figures and Tables

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References

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Comparative discriminative stimulus effects of 5-methoxy-N,N-dimethyltryptamine and LSD.

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Discriminative stimulus properties of l-5-hydroxytryptophan: Behavioral evidence for multiple serotonin receptors

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The role of dopamine and serotonin in the discriminative stimulus effects of lisuride.

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The Journal of pharmacology and experimental…
1982

Discriminative stimulus properties of the hallucinogenic agent DOM.

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Factors regulating drug cue sensitivity: limits of discriminability and the role of a progressively decreasing training dose in fentanyl-saline discrimination.

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Discriminative stimulus properties of pizotifen maleate (BC105): a putative serotonin antagonist

Abstract

4 Figures and Tables

Topics

Cited By

The Selective Serotonin2A Receptor Antagonist, MDL100,907, Elicits a Specific Interoceptive Cue in Rats

Discriminative stimulus effects of serotonin agonists, neutral antagonists, and inverse agonists in pigeons: perspectives on intrinsic efficacy measurements in vivo

Further evidence that the delayed temporal dopaminergic effects of LSD are mediated by a mechanism different than the first temporal phase of action.

In vivo Schild regression analyses using nonselective 5-HT2C receptor antagonists in a rat operant behavioral assay

Stimulus effects of ibogaine in rats trained with yohimbine, DOM, or LSD.

Trends in drug discrimination research analysed with a cross-indexed bibliography, 1984–1987

References

The discriminative stimulus properties of LSD: mechanisms of action.

The discriminative stimulus properties of mepyramine.

( I 981 ) Speculations on the mechanism of action of hallucinogenic indolealkylamines

Drug-induced discrimination: a description of the paradigm and a review of its specific application to the study of hallucinogenic agents.

A drug discrimination analys~s of/ysergic acid diethylamicle (LSD): tn vivo agonist and antagonist effects of purported 5-hydroxytryptamine antagonists and of pirenperone, a LSD antagonist

Comparative discriminative stimulus effects of 5-methoxy-N,N-dimethyltryptamine and LSD.

Discriminative stimulus properties of l-5-hydroxytryptophan: Behavioral evidence for multiple serotonin receptors

The role of dopamine and serotonin in the discriminative stimulus effects of lisuride.

Discriminative stimulus properties of the hallucinogenic agent DOM.

Factors regulating drug cue sensitivity: limits of discriminability and the role of a progressively decreasing training dose in fentanyl-saline discrimination.

Presentations referencing similar topics

Discriminative stimulus properties of pizotifen maleate (BC105): a putative serotonin antagonist

Abstract

4 Figures and Tables

Topics

Cited By

The Selective Serotonin2A Receptor Antagonist, MDL100,907, Elicits a Specific Interoceptive Cue in Rats

Discriminative stimulus effects of serotonin agonists, neutral antagonists, and inverse agonists in pigeons: perspectives on intrinsic efficacy measurements in vivo

Further evidence that the delayed temporal dopaminergic effects of LSD are mediated by a mechanism different than the first temporal phase of action.

In vivo Schild regression analyses using nonselective 5-HT2C receptor antagonists in a rat operant behavioral assay

Stimulus effects of ibogaine in rats trained with yohimbine, DOM, or LSD.

Trends in drug discrimination research analysed with a cross-indexed bibliography, 1984–1987

References

The discriminative stimulus properties of LSD: mechanisms of action.

The discriminative stimulus properties of mepyramine.

( I 981 ) Speculations on the mechanism of action of hallucinogenic indolealkylamines

Drug-induced discrimination: a description of the paradigm and a review of its specific application to the study of hallucinogenic agents.

A drug discrimination analys~s of/ysergic acid diethylamicle (LSD): tn vivo agonist and antagonist effects of purported 5-hydroxytryptamine antagonists and of pirenperone, a LSD antagonist

Comparative discriminative stimulus effects of 5-methoxy-N,N-dimethyltryptamine and LSD.

Discriminative stimulus properties of l-5-hydroxytryptophan: Behavioral evidence for multiple serotonin receptors

The role of dopamine and serotonin in the discriminative stimulus effects of lisuride.

Discriminative stimulus properties of the hallucinogenic agent DOM.

Factors regulating drug cue sensitivity: limits of discriminability and the role of a progressively decreasing training dose in fentanyl-saline discrimination.

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