Discriminative stimulus properties of pizotifen maleate (BC105): a putative serotonin antagonist

Abstract

Rats were trained to discriminate the putative serotonin (5-HT) antagonist, pizotifen maleate (BC105), from saline using a two-lever drug discrimination paradigm. Pizotifen maleate (6 mg/kg, 14.6 μmol/kg, IP) or saline was administered 55 min prior to the operant training session. The pizotifen discriminative stimulus (DS) had a rapid onset (less than 7 min… (More)
DOI: 10.1007/BF00429735

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