Discriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analog

Abstract

To characterize in vivo the high-affinity CB1 cannabinoid receptor (CB1R) selective anandamide analog AM1346 [alkoxyacid amide of N-eicosa-tetraenylamine] using drug discrimination. Substitution tests involved Δ9-tetrahydrocannabinol (Δ9-THC) and R-(+)-methanandamide (mAEA), a metabolically stable analog of anandamide (AEA), as well as the CB1R antagonist… (More)
DOI: 10.1007/s00213-008-1199-3

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@article{Jrbe2008DiscriminativeSF, title={Discriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analog}, author={Torbj{\"{o}rn U. C. J{\"a}rbe and Chen Li and Qian Liu and Alexandros Makriyannis}, journal={Psychopharmacology}, year={2008}, volume={203}, pages={229-239} }