Discriminative stimulus and subjective effects of theobromine and caffeine in humans

@article{Mumford1994DiscriminativeSA,
  title={Discriminative stimulus and subjective effects of theobromine and caffeine in humans},
  author={Geoffrey K. Mumford and Suzette M. Evans and Barbara J. Kaminski and Kenzie L Preston and Christine A. Sannerud and Kenneth P. Silverman and Roland R Griffiths},
  journal={Psychopharmacology},
  year={1994},
  volume={115},
  pages={1-8}
}
Theobromine versus placebo discrimination and caffeine versus placebo discrimination were studied in two consecutive experiments in seven volunteers who abstained from methylxanthines. Daily sessions involved PO double-blind ingestion of two sets of capsules sequentially, one of which contained drug and the other placebo. Subjects attempted to identify, and were later informed, which set of capsules contained the drug. In each experiment subjects were exposed to progressively lower doses. Five… CONTINUE READING
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