Discriminative stimulus and antinociceptive effects of dihydroetorphine in rhesus monkeys

@article{Gerak2003DiscriminativeSA,
  title={Discriminative stimulus and antinociceptive effects of dihydroetorphine in rhesus monkeys},
  author={L. R. Gerak and C. Gauthier and C. France},
  journal={Psychopharmacology},
  year={2003},
  volume={166},
  pages={351-359}
}
  • L. R. Gerak, C. Gauthier, C. France
  • Published 2003
  • Psychology, Medicine
  • Psychopharmacology
  • Abstract Rationale. Although dihydroetorphine has µ opioid agonist activity there is evidence to suggest that it is not identical to that of morphine. Objective. This study compared dihydroetorphine to other opioids under behavioral conditions that are sensitive to µ opioid agonism. Methods. The acute effects of dihydroetorphine, etorphine and morphine were evaluated using two procedures. In one procedure, monkeys received 3.2 mg/kg per day of morphine and discriminated naltrexone from saline… CONTINUE READING
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    References

    SHOWING 1-10 OF 32 REFERENCES
    Antinociceptive and respiratory effects of nalbuphine in rhesus monkeys.
    • 62
    Potent reinforcing effects of dihydroetorphine in rats.
    • 15
    Discriminative stimulus effects of nalbuphine in rhesus monkeys.
    • 36
    • Highly Influential
    Agonist and antagonist properties of dihydroetorphine for μ-opioid receptors in mice
    • 7
    • Highly Influential
    Etorphines: mu-opioid receptor-selective antinociception and low physical dependence capacity.
    • 51
    • Highly Influential
    Evaluation of the discriminative stimulus and reinforcing effects of dihydroetorphine.
    • 15
    • Highly Influential
    Discriminative stimulus effects of naltrexone in morphine-treated rhesus monkeys.
    • C. France, J. Woods
    • Psychology, Medicine
    • The Journal of pharmacology and experimental therapeutics
    • 1989
    • 67
    Antinociceptive effect of dihydroetorphine and its tolerance/dependence liability in mice.
    • 21
    • Highly Influential
    Discriminative stimulus effects of reversible and irreversible opiate agonists: morphine, oxymorphazone and buprenorphine.
    • 46
    Buprenorphine antagonism of mu opioids in the rhesus monkey tail-withdrawal procedure.
    • 74