Discriminative Stimulus Properties of Nicotine : Approaches to Evaluating Potential Nicotinic Receptor Agonists and Antagonists

@inproceedings{JennyDiscriminativeSP,
  title={Discriminative Stimulus Properties of Nicotine : Approaches to Evaluating Potential Nicotinic Receptor Agonists and Antagonists},
  author={Jenny and 1. and Wiley and John R. James and John A. Rosecrans}
}
The prototypic nicotinic acetylcholinergic receptor (nAChR) agonist, nicotine, is one of the primary psychoactive ingredients of tobacco. This review examines the effects of nicotine and similar compounds in nicotine discrimination procedures, a paradigm in which the subjective effects of nicotine can be modeled in animals. Results of these studies have shown that the discriminative stimulus effects of nicotine are shared by nicotine analogues and by the novel nicotinic agonists, epibatidine… CONTINUE READING

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