Discrimination of benign and malignant thyroid nodules by molecular profiling.

  title={Discrimination of benign and malignant thyroid nodules by molecular profiling.},
  author={David J. Finley and Baixin Zhu and Catherine B. Barden and Thomas J. Fahey},
  journal={Annals of surgery},
  volume={240 3},
  pages={425-36; discussion 436-7}
BACKGROUND The evaluation of thyroid nodules by fine-needle aspiration has been the standard for almost 30 years, despite significant shortcomings in sensitivity and specificity. Recent data from our laboratory have suggested that molecular profiling permits the discrimination of specific types of thyroid nodules. These studies were undertaken to determine whether molecular profiling can discriminate between benign and malignant thyroid nodules with the necessary sensitivity and specificity… CONTINUE READING
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