Discrimination learning alters the distribution of protein kinase C in the hippocampus of rats.

@article{Olds1990DiscriminationLA,
  title={Discrimination learning alters the distribution of protein kinase C in the hippocampus of rats.},
  author={James L. Olds and S Golski and Donna L. McPhie and David S. Olton and Mortimer Mishkin and Daniel L. Alkon},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1990},
  volume={10 11},
  pages={3707-13}
}
Protein kinase C (PKC), an enzyme that plays an essential role in eukaryotic cell regulation (Nishizuka, 1988; Huang et al., 1989), is critical to memory storage processes both in the marine snail Hermissenda crassicornis and in the rabbit (Alkon et al., 1988; Bank et al., 1988; Olds et al., 1989). Specifically, activation of PKC mimics neurobiological correlates of classical conditioning in both Hermissenda and the rabbit, and the distribution of the enzyme within the rabbit hippocampus… CONTINUE READING