Discrimination between exosomes and HIV-1: purification of both vesicles from cell-free supernatants.

  title={Discrimination between exosomes and HIV-1: purification of both vesicles from cell-free supernatants.},
  author={R{\'e}jean Cantin and Juliette Diou and Dave Belanger and Alexandre M Tremblay and Caroline Gilbert},
  journal={Journal of immunological methods},
  volume={338 1-2},
Although enveloped retroviruses bud from the cell surface of T lymphocytes, they use the endocytic pathway and the internal membrane of multivesicular bodies for their assembly and release from macrophages and dendritic cells (DCs). Exosomes, physiological nanoparticles produced by hematopoietic cells, egress from this same pathway and are similar to retroviruses in terms of size, density, the molecules they incorporate and their ability to activate immune cells. Retroviruses are therefore… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 84 extracted citations

HIV-1 IN/Pol recruits LEDGF/p75 into viral particles

Retrovirology • 2014
View 6 Excerpts
Highly Influenced

Exosomes Decrease in vitro Infectivity of HIV-1 Preparations: Implication for CD4+T Lymphocyte Depletion in vivo

Burelout Chantal, Proulx Sophie, Simard Sébastien
View 7 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…