Discrimination between celiac and other gastrointestinal disorders in childhood by rapid human lymphocyte antigen typing.

@article{Sacchetti1998DiscriminationBC,
  title={Discrimination between celiac and other gastrointestinal disorders in childhood by rapid human lymphocyte antigen typing.},
  author={Lucia Sacchetti and Giuseppe Calcagno and Anna Ferrajolo and C. Sarrantonio and Riccardo Troncone and M. Micillo and Salvatore Auricchio and Francesco Salvatore},
  journal={Clinical chemistry},
  year={1998},
  volume={44 8 Pt 1},
  pages={
          1755-7
        }
}
Celiac disease (CD) is a genetically complex, multifactorial immune-mediated disease (1). The intestinal damage that characterizes the disorder is induced by dietary gluten ingestion in susceptible individuals (1). A specific HLA DQA10501 / DQB10201 heterodimer, or in a few cases, the HLA DRB104 alleles, is associated with the disease (2). In fact, when presented by these HLA molecules, gluten-derived peptides cause T-cell activation in the intestinal mucosa, which is followed by cytokine… CONTINUE READING

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MicroRNAs: an epigenetic tool to study celiac disease.

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