Discrimination between benign and malignant adnexal masses by specialist ultrasound examination versus serum CA-125.

@article{Calster2007DiscriminationBB,
  title={Discrimination between benign and malignant adnexal masses by specialist ultrasound examination versus serum CA-125.},
  author={Ben Van Calster and Dirk Timmerman and Tom Bourne and Antonia C. Testa and Caroline Van Holsbeke and Ekaterini Domali and Davor Jurkovic and Patrick Neven and Sabine Van Huffel and Lil Valentin},
  journal={Journal of the National Cancer Institute},
  year={2007},
  volume={99 22},
  pages={1706-14}
}
BACKGROUND Subjective evaluation of gray-scale and Doppler ultrasound findings (i.e., pattern recognition) by an experienced examiner and preoperative serum levels of CA-125 can both discriminate benign from malignant adnexal (i.e., ovarian, paraovarian, or tubal) masses. We compared the diagnostic performance of these methods in a large multicenter study. METHODS In a prospective multicenter study--the International Ovarian Tumor Analysis--1066 women with a persistent adnexal mass underwent… CONTINUE READING