Discriminating accuracy of medial temporal lobe volumetry and fMRI in mild cognitive impairment.

@article{Jauhiainen2009DiscriminatingAO,
  title={Discriminating accuracy of medial temporal lobe volumetry and fMRI in mild cognitive impairment.},
  author={Anne M. Jauhiainen and Maija Pihlajam{\"a}ki and Susanna Tervo and Eini Niskanen and Heikki Tanila and Tuomo H{\"a}nninen and Ritva L. Vanninen and Hilkka Soininen},
  journal={Hippocampus},
  year={2009},
  volume={19 2},
  pages={166-75}
}
We investigated structural and functional changes in the medial temporal lobe (MTL) using magnetic resonance imaging (MRI) and compared the discriminative power of these measures with neuropsychological testing in mild cognitive impairment (MCI) and Alzheimer's disease (AD). Functional MRI (fMRI) was performed in 21 elderly controls, 14 MCI subjects, and 15 mild AD patients during encoding and cued retrieval of word-picture pairs. A region-of-interest-based approach in SPM2 was used to extract… CONTINUE READING

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