Discrete synaptic states define a major mechanism of synapse plasticity

@article{Montgomery2004DiscreteSS,
  title={Discrete synaptic states define a major mechanism of synapse plasticity},
  author={Johanna M. Montgomery and Daniel V. Madison},
  journal={Trends in Neurosciences},
  year={2004},
  volume={27},
  pages={744-750}
}
Synapses can change their strength in response to afferent activity, a property that might underlie a variety of neural processes such as learning, network synaptic weighting, synapse formation and pruning. Recent work has shown that synapses change their strength by jumping between discrete mechanistic states, rather than by simply moving up and down in a continuum of efficacy. Coincident with this, studies have provided a framework for understanding the potential mechanistic underpinnings of… Expand

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