Discrete structure of van der Waals domains in globular proteins.

@article{Berezovsky2003DiscreteSO,
  title={Discrete structure of van der Waals domains in globular proteins.},
  author={Igor N. Berezovsky},
  journal={Protein engineering},
  year={2003},
  volume={16 3},
  pages={161-7}
}
Most globular proteins are divisible by domains, distinct substructures of the globule. The notion of hierarchy of the domains was introduced earlier via van der Waals energy profiles that allow one to subdivide the proteins into domains (subdomains). The question remains open as to what is the possible structural connection of the energy profiles. The recent discovery of the loop-n-lock elements in the globular proteins suggests such a structural connection. A direct comparison of the… CONTINUE READING