Discrete particle simulations predicting mixing behavior of solid substrate particles in a rotating drum fermenter.

@article{Schutyser2001DiscretePS,
  title={Discrete particle simulations predicting mixing behavior of solid substrate particles in a rotating drum fermenter.},
  author={Maarten A. I. Schutyser and Johan T Padding and Frans J Weber and W. J. Briels and Arjen Rinzema and Remko Marcel Boom},
  journal={Biotechnology and bioengineering},
  year={2001},
  volume={75 6},
  pages={666-75}
}
A soft-sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid-state fermentation. In this approach, forces acting on and subsequent motion of individual particles can be predicted. The (2D) simulations were qualitatively and quantitatively validated by mixing experiments using video and image analysis techniques. It was found that the simulations successfully predicted the mixing progress as a function of the degree of… CONTINUE READING