Discrepancy in prostate cancer localization between biopsy and prostatectomy specimens in patients with unilateral positive biopsy: implications for focal therapy.

@article{Sinnott2012DiscrepancyIP,
  title={Discrepancy in prostate cancer localization between biopsy and prostatectomy specimens in patients with unilateral positive biopsy: implications for focal therapy.},
  author={Michael Sinnott and Sara Moscovita Falzarano and Adri{\'a}n V Hern{\'a}ndez and J. Stephen Jones and Eric A Klein and Ming Zhou and Cristina Magi-Galluzzi},
  journal={The Prostate},
  year={2012},
  volume={72 11},
  pages={1179-86}
}
BACKGROUND Unilateral ablative strategy success depends on reliable prediction of prostate cancer (PCA) location. We evaluated the discrepancy in PCA localization between unilateral positive biopsy (PBx) and radical prostatectomy (RP). METHODS Between 2004 and 2008, 431 patients were diagnosed with unilateral PCA by 12-core PBx; 179 underwent RP and constituted our study cohort. Specimens were reviewed to map tumor outline and determine number of cancer foci, tumor volume, Gleason score (GS… CONTINUE READING