Discovery of the hepatitis C virus.

  title={Discovery of the hepatitis C virus.},
  author={Michael Houghton},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  volume={29 Suppl 1},
After nearly 6 years of intensive investigations between 1982 and 1988 in my laboratory at Chiron corporation, in which numerous molecular biological methods were used to investigate the viral aetiology of parenterally transmitted non-A, non-B viral hepatitis (NANBH), a single cDNA clone (5-1-1) was isolated that was shown to be derived from a new flavi-like virus, termed the hepatitis C virus (HCV). After screening hundreds of millions of bacterial cDNA clones derived from different liver and… CONTINUE READING