Discovery of superoxide reductase: an historical perspective

  title={Discovery of superoxide reductase: an historical perspective},
  author={Vincent Nivi{\`e}re and Marc Fontecave},
  journal={JBIC Journal of Biological Inorganic Chemistry},
For more than 30 years, the only enzymatic system known to catalyze the elimination of superoxide was superoxide dismutase, SOD. SOD has been found in almost all organisms living in the presence of oxygen, including some anaerobic bacteria, supporting the notion that superoxide is a key and general component of oxidative stress. Recently, a new concept in… CONTINUE READING