Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distribution.

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@article{Pfefferkorn2011DiscoveryON, title={Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distribution.}, author={Jeffrey A. Pfefferkorn and John Litchfield and Richard H. Hutchings and Xue-min Cheng and Scott D Larsen and Bruce J. Auerbach and Mark R Bush and Chitase Lee and Noe O Erasga and Daniel M Bowles and David C Boyles and Gina H Lu and Catherine Sekerke and Valerie Askew and Jeffrey C . Hanselman and Lisa Y. Dillon and Zhiwu Lin and Andrew Robertson and Karl R. Olsen and C. Boustany and Karen A Atkinson and Theunis C. Goosen and Vaishali P Sahasrabudhe and Jonathan Chupka and David B. Duignan and Bo Feng and Renato J. Scialis and Emi Kimoto and Yi-an Bi and Yurong Lai and Ayman F. El-Kattan and Rebecca Bakker-Arkema and P. E. Barclay and Erick K Kindt and Vu Quynh Anh Le and Jaap W. Mandema and Mark A . Milad and Bradley D. Tait and Robert M. Kennedy and Bharat K Trivedi and Mark C. Kowala}, journal={Bioorganic & medicinal chemistry letters}, year={2011}, volume={21 9}, pages={2725-31} }