Discovery of nitric oxide and cyclic GMP in cell signaling and their role in drug development

@article{Murad2012DiscoveryON,
  title={Discovery of nitric oxide and cyclic GMP in cell signaling and their role in drug development},
  author={F. Murad},
  journal={Molecular Neurodegeneration},
  year={2012},
  volume={7},
  pages={L1 - L1}
}
  • F. Murad
  • Published 2012
  • Chemistry
  • Molecular Neurodegeneration
The role of nitric oxide in cellular signaling in the past three decades has become one of the most rapidly growing areas in biology. Nitric oxide is a gas and a free radical with an unshared electron that can regulate an ever-growing list of biological processes. Nitric oxide is formed from L-arginine by a family of enzymes called nitric oxide synthases. These enzymes have a complex requirement for a number of cofactors and regulators including NADPH, tetrahydrobioterin, flavins, calmodulin… Expand

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