Discovery of a novel genetic susceptibility locus on X chromosome for systemic lupus erythematosus

@inproceedings{Zhu2015DiscoveryOA,
  title={Discovery of a novel genetic susceptibility locus on X chromosome for systemic lupus erythematosus},
  author={Zhengwei Zhu and Zhuoyuan Liang and Herty Liany and Chao Yang and Leilei Wen and Zhiming Lin and Yujun Sheng and Yan Lin and Lei Ye and Yuyan Cheng and Yan Chang and Lu Liu and Lulu Yang and Yinjuan Shi and Changbing Shen and Fusheng Zhou and Xiaodong Zheng and Jun Zhu and Bo Liang and Yantao Ding and Yi Zhou and Xianyong Yin and Huayang Y Tang and Xianbo Zuo and Liangdan Sun and Jin-Xin Bei and Jianping Liu and Sen Yang and Wanling Yang and Yong Cui and Xuejun Zhang},
  booktitle={Arthritis research & therapy},
  year={2015}
}
INTRODUCTION Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease affecting predominantly females. To discover additional genetic risk variants for SLE on the X chromosome, we performed a follow-up study of our previously published genome-wide association study (GWAS) data set in this study. METHODS Twelve single nucleotide polymorphisms (SNPs) within novel or unpublished loci with P-value < 1.00 × 10(-02) were selected for genotype with a total of 2,442 cases and 2… CONTINUE READING

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Systemic lupus erythematosus ( SLE ) is an autoimmune connective tissue disease affecting predominantly females .
Systemic lupus erythematosus ( SLE ) is an autoimmune connective tissue disease affecting predominantly females .
Systemic lupus erythematosus ( SLE ) is an autoimmune connective tissue disease affecting predominantly females .
Systemic lupus erythematosus ( SLE ) is an autoimmune connective tissue disease affecting predominantly females .
Systemic lupus erythematosus ( SLE ) is an autoimmune connective tissue disease affecting predominantly females .
Systemic lupus erythematosus ( SLE ) is an autoimmune connective tissue disease affecting predominantly females .
Systemic lupus erythematosus ( SLE ) is an autoimmune connective tissue disease affecting predominantly females .
Systemic lupus erythematosus ( SLE ) is an autoimmune connective tissue disease affecting predominantly females .
Twelve single nucleotide polymorphisms ( SNPs ) within novel or unpublished loci with P - value < 1.00 × 10(-02 ) were selected for genotype with a total of 2,442 cases and 2,798 controls(including 1,156 cases and 2,330 controls from central China , 1,012 cases and 335 controls from southern China and 274 cases and 133 controls from northern China ) using Sequenom Massarry system .
Twelve single nucleotide polymorphisms ( SNPs ) within novel or unpublished loci with P - value < 1.00 × 10(-02 ) were selected for genotype with a total of 2,442 cases and 2,798 controls(including 1,156 cases and 2,330 controls from central China , 1,012 cases and 335 controls from southern China and 274 cases and 133 controls from northern China ) using Sequenom Massarry system .
Twelve single nucleotide polymorphisms ( SNPs ) within novel or unpublished loci with P - value < 1.00 × 10(-02 ) were selected for genotype with a total of 2,442 cases and 2,798 controls(including 1,156 cases and 2,330 controls from central China , 1,012 cases and 335 controls from southern China and 274 cases and 133 controls from northern China ) using Sequenom Massarry system .
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