Discovery of Influenza A virus neuraminidase inhibitors using support vector machine and Naïve Bayesian models

Neuraminidase (NA) is a critical enzyme in the life cycle of influenza virus, which is known as a successful paradigm in the design of anti-influenza agents. However, to date there are no classification models for the virtual screening of NA inhibitors. In this work, we built support vector machine and Naïve Bayesian models of NA inhibitors and non… CONTINUE READING