Discovery of DiPeptidyl Peptidase-4 Gene Variants and the Associations with Efficacy of Vildagliptin in Patients with Type 2 Diabetes - A Pilot Study

@inproceedings{Kwon2013DiscoveryOD,
  title={Discovery of DiPeptidyl Peptidase-4 Gene Variants and the Associations with Efficacy of Vildagliptin in Patients with Type 2 Diabetes - A Pilot Study},
  author={Obin Kwon and Eun Yeong Choe and Younjeong Choi and Hyung Jun Kim and Hye Jin Wang and Hyeyoung Lee and Chul Hoon Kim and Eun Seok Kang},
  year={2013}
}
Diabetes mellitus is growing global pandemic [1], causing microand macrovascular complications [2]. Compared with type 1 diabetes due to an absolute deficiency of insulin secretion, type 2 diabetes, a much more prevalent category, is due to combination of resistance to insulin action and an inadequate compensatory insulin secretory response [3]. Metformin is the preferred initial pharmacological agent for type 2 diabetes, and if metformin monotherapy at maximal tolerated dose does not achieve… CONTINUE READING

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