Discovery of (10R)-7-Amino-12-Fluoro-2,10,16-Trimethyl-15-Oxo-10,15,16,17-Tetrahydro-2H-8,4-(Metheno)Pyrazolo[4,3-H][2,5,11]Benzoxadiazacyclotetradecine-3-Carbonitrile (Pf-06463922), a Macrocyclic Inhibitor of Alk/Ros1 with Pre-Clinical Brain Exposure and Broad Spectrum Potency Against Alk-Resistant

@inproceedings{Johnson2014DiscoveryO,
  title={Discovery of (10R)-7-Amino-12-Fluoro-2,10,16-Trimethyl-15-Oxo-10,15,16,17-Tetrahydro-2H-8,4-(Metheno)Pyrazolo[4,3-H][2,5,11]Benzoxadiazacyclotetradecine-3-Carbonitrile (Pf-06463922), a Macrocyclic Inhibitor of Alk/Ros1 with Pre-Clinical Brain Exposure and Broad Spectrum Potency Against Alk-Resistant},
  author={Ted W Johnson and Paul Richardson and Simon Bailey and Alexei Brooun and Benjamin J. Burke and Michael Johnson and J. Jean Cui and Judith Gail Deal and Ya-li Deng and Dac M. Dinh and Lars D. Engstrom and Yang Bai and Jacqui Elizabeth Hoffman and Robert Louis Hoffman and Qinhua Huang and John Charles Kath and Stephan James Cripps and Henry Lam and Justine L. Lam and Phuong Thi Quy Le and Laura Lingardo and Weidong Liu and Mctigue and Theodore Otto Johnson and Neal W. Sach and Tod Smeal and Graham Frank Smith and Albert E. Stewart and Sergei L Timofeevski and Huichun Zhu and Jinjiang Zhu and Helen Y. Zou and Martin Paul Edwards},
  year={2014}
}

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