Discovery and identification of alpha-defensins as low abundant, tumor-derived serum markers in colorectal cancer.

Abstract

BACKGROUND & AIMS Although colorectal cancer is one of the best characterized tumors with regard to the multistep genetic progression, it remains one of the most frequent and deadly neoplasms in Western countries. This is mainly due to the fact that, up to now, no clinically relevant serum markers could be established in an early routine diagnostic… (More)

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@article{Melle2005DiscoveryAI, title={Discovery and identification of alpha-defensins as low abundant, tumor-derived serum markers in colorectal cancer.}, author={Christian Melle and G{\"{u}nther Ernst and Bettina Schimmel and Annett Bleul and Heike Thieme and Roland Kaufmann and Henning Mothes and Utz Settmacher and Uwe Claussen and K J Halbhuber and Ferdinand von Eggeling}, journal={Gastroenterology}, year={2005}, volume={129 1}, pages={66-73} }