Discovery and clinical application of a novel prostate cancer marker: alpha-methylacyl CoA racemase (P504S).

@article{Jiang2004DiscoveryAC,
  title={Discovery and clinical application of a novel prostate cancer marker: alpha-methylacyl CoA racemase (P504S).},
  author={Zhong Yi Jiang and BruceA. Woda and Chunghsi J. Wu and Ximing J. Yang},
  journal={American journal of clinical pathology},
  year={2004},
  volume={122 2},
  pages={
          275-89
        }
}
The recent discovery of the overexpression of P504S/alpha-methylacyl coenzyme A racemase (AMACR) in prostate cancer is a successful example of translating an advanced molecular finding into clinical practice. AMACR (P504S) has been proven to be one of the few biomarkers that can help distinguish cancer from benign cells, with high sensitivity and specificity for prostate carcinoma. It is the first gene identified by the analysis of complementary DNA microarray profiles from prostate tissue to… CONTINUE READING
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