Cannabidiol in clinical and preclinical anxiety research. A systematic review into concentration–effect relations using the IB-de-risk tool
- Biology, PsychologyJournal of psychopharmacology
A straightforward dosing recommendation was not possible, given variable concentration–effect relations across species, and no consistent linear effect of CBD on anxiety reduction, which raises questions about the broad use as a drug for anxiety.
MODULATION OF ENDOCANNABINOID SYSTEM IN EXPERIMENTAL ENDOTOXEMIA
Using nanofiltration membranes for the recovery of phosphorous with a second type of technology for theovery of nitrogen is suggest to be a viable process.
“The Two Sides of the Same Coin”—Medical Cannabis, Cannabinoids and Immunity: Pros and Cons Explained
- Biology, MedicinePharmaceutics
It is proposed that much is still unknown about adverse reactions to cannabis use, and its integration with medical treatment should be conducted cautiously with consideration of the individual patient, effector cells, microenvironment, and the immune system.
Cannabigerol: a bibliometric overview and review of research on an important phytocannabinoid
- BiologyPhytochemistry Reviews
In-depth analysis of the published literature revealed that clinical trials establishing the efficacy, safety and side-effects of CBG therapy in specific disease conditions are limited, as well as industry-friendly quality control procedures for CBG-enriched cannabis extracts.
Terpenes/Terpenoids in Cannabis: Are They Important?
- ChemistryMedical Cannabis and Cannabinoids
The main terpenes/terpenoids and their abundance in the samples were evaluated and will be helpful in the next evaluation of these compound in mixture with cannabinoids and their importance in medical treatment.
Substance Use Disorders
- MedicinePerinatal Psychopharmacology
The present chapter aims at providing a comprehensive overview on birth defects, foetal malformations, teratogenic risk and perinatal complications related to the consumption of cannabinoids, opioids and psychostimulant drugs during pregnancy.
Synthesis of novel 2-(1-adamantanylcarboxamido)thiophene derivatives. Selective cannabinoid type 2 (CB2) receptor agonists as potential agents for the treatment of skin inflammatory disease.
- Chemistry, BiologyEuropean journal of medicinal chemistry
Determination of the Endocannabinoids Anandamide and 2-Arachidonoyl Glycerol with Gas Chromatography-Mass Spectrometry: Analytical and Preanalytical Challenges and Pitfalls
- MedicineMedical Cannabis and Cannabinoids
Overall, limited in vitro and/or in vivo/ex vivo chemical stability of endocannabinoids has to be taken into account.
Cannabis through the looking glass: chemo- and enantio-selective separation of phytocannabinoids by enantioselective ultra high performance supercritical fluid chromatography.
- ChemistryChemical communications
An enantioselective UHPSFC method is developed to determine the enantiomeric excess of (-)-Δ9-THC in medicinal marijuana (Bedrocan®) and the ee was high, but the concentration of the (+)-enantiomer was not negligible, and it is worth a systematic evaluation of bioactivity.
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Structure of Cannabidiol. VI. Isomerization of Cannabidiol to Tetrahydrocannabinol, a Physiologically Active Product. Conversion of Cannabidiol to Cannabinol1
STRUCTURE OF CANNABIDIOL. VIII. POSITION OF THE DOUBLE BONDS IN CANNABIDIOL. MARIHUANA ACTIVITY OF TETRAHYDROCANNABINOLS
Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish
strongly solvated than triple ions,lb-5 the difference being greater for cations of smaller radii, leading to a trend to smaller K with decreasing cationic radii. Both effects, in opposite…
Conversion of cannabidiol to a product with marihuana activity A type reaction for synthesis of analogous substances Conversion of cannabidiol to cannabinol
Structure of Cannabidiol. VII. A Method of Synthesis of a Tetrahydrocannabinol which Possesses Marihuana Activity1