Discovering the phosphoproteome of the hydrophobic cytochrome c oxidase membrane protein complex.

Abstract

Many cellular processes are regulated by reversible phosphorylation to change the activity state of proteins. One example is cytochrome c oxidase (COX) with its important function for energy metabolism in the mitochondria. The phosphorylation of this enzyme is a prerequisite for the allosteric ATP-inhibition and therefore necessary to adapt energy… (More)
DOI: 10.1007/978-1-61779-885-6_21

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