Discovering putative prion sequences in complete proteomes using probabilistic representations of Q/N-rich domains

@inproceedings{Angarica2012DiscoveringPP,
  title={Discovering putative prion sequences in complete proteomes using probabilistic representations of Q/N-rich domains},
  author={Vladimir Espinosa Angarica and Salvador Ventura and Javier Sancho},
  booktitle={BMC Genomics},
  year={2012}
}
Prion proteins conform a special class among amyloids due to their ability to transmit aggregative folds. Prions are known to act as infectious agents in neurodegenerative diseases in animals, or as key elements in transcription and translation processes in yeast. It has been suggested that prions contain specific sequential domains with distinctive amino acid composition and physicochemical properties that allow them to control the switch between soluble and β-sheet aggregated states. Those… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
24 Citations
101 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 101 references

Similar Papers

Loading similar papers…