Discovering gene-environment interactions in the post-genomic era.

@article{Naidoo2009DiscoveringGI,
  title={Discovering gene-environment interactions in the post-genomic era.},
  author={Nasheen Naidoo and Kee Seng Chia},
  journal={Journal of preventive medicine and public health = Yebang Uihakhoe chi},
  year={2009},
  volume={42 6},
  pages={356-9}
}
In the more than 100 genome wide association studies (GWAS) conducted in the past 5 years, more than 250 genetic loci contributing to more than 40 common diseases and traits have been identified. Whilst many genes have been linked to a trait, both their individual and combined effects are small and unable to explain earlier estimates of heritability. Given… CONTINUE READING