Discovering cooperative biomarkers for heterogeneous complex disease diagnoses

@article{Sun2019DiscoveringCB,
  title={Discovering cooperative biomarkers for heterogeneous complex disease diagnoses},
  author={Duanchen Sun and Xian-Wen Ren and Eszter Ari and Tam{\'a}s Korcsm{\'a}ros and P{\'e}ter Csermely and Ling-Yun Wu},
  journal={Briefings in bioinformatics},
  year={2019},
  volume={20 1},
  pages={
          89-101
        }
}
Biomarkers with high reproducibility and accurate prediction performance can contribute to comprehending the underlying pathogenesis of related complex diseases and further facilitate disease diagnosis and therapy. Techniques integrating gene expression profiles and biological networks for the identification of network-based disease biomarkers are receiving increasing interest. The biomarkers for heterogeneous diseases often exhibit strong cooperative effects, which implies that a set of genes… CONTINUE READING

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