Discoveries, metabolic roles and diseases of mitochondrial carriers: A review.

@article{Palmieri2016DiscoveriesMR,
  title={Discoveries, metabolic roles and diseases of mitochondrial carriers: A review.},
  author={Ferdinando Palmieri and Magnus Monn{\'e}},
  journal={Biochimica et biophysica acta},
  year={2016},
  volume={1863 10},
  pages={
          2362-78
        }
}
Mitochondrial carriers (MCs) are a superfamily of nuclear-encoded proteins that are mostly localized in the inner mitochondrial membrane and transport numerous metabolites, nucleotides, cofactors and inorganic anions. Their unique sequence features, i.e., a tripartite structure, six transmembrane α-helices and a three-fold repeated signature motif, allow MCs to be easily recognized. This review describes how the functions of MCs from Saccharomyces cerevisiae, Homo sapiens and Arabidopsis… CONTINUE READING

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