Discorhabdins revisited: cytotoxic alkaloids from southern australian marine sponges of the genera Higginsia and Spongosorites.
@article{ElNaggar2009DiscorhabdinsRC, title={Discorhabdins revisited: cytotoxic alkaloids from southern australian marine sponges of the genera Higginsia and Spongosorites.}, author={M. El-Naggar and R. Capon}, journal={Journal of natural products}, year={2009}, volume={72 3}, pages={ 460-4 } }
Chemical analysis of southern Australian marine sponges of the genera Higginsia and Spongosorites has yielded examples of the discorhabdin class of alkaloids. These include the known metabolites (+)-discorhabdin A (1), (+)-discorhabdin D (2), makaluvamine J (6), and damirone A (7), together with four new analogues, (+)-dihydrodiscorhabdin A (3), (+)-debromodiscorhabdin A (4), (+)-dihydrodiscorhabdin L (8), and (+)-discorhabdin X (5), with the latter compound being the first reported example of… Expand
Topics from this paper
22 Citations
New natural products in the discorhabdin A- and B-series from New Zealand-sourced Latrunculia spp. sponges
- Chemistry
- 2009
- 15
Discorhabdin alkaloids from Antarctic Latrunculia spp. sponges as a new class of cholinesterase inhibitors.
- Chemistry, Medicine
- European journal of medicinal chemistry
- 2017
- 17
Synthesis of the Marine Pyrroloiminoquinone Alkaloids, Discorhabdins
- Biology, Medicine
- Marine drugs
- 2010
- 15
- PDF
The synthetic and biological studies of discorhabdins and related compounds.
- Chemistry, Medicine
- Organic & biomolecular chemistry
- 2011
- 21
- PDF
Chemistry, Chemotaxonomy and Biological Activity of the Latrunculid Sponges (Order Poecilosclerida, Family Latrunculiidae)
- Medicine
- Marine drugs
- 2021
- PDF
Exploration of the influence of spiro-dienone moiety on biological activity of the cytotoxic marine alkaloid discorhabdin P
- Chemistry
- 2017
- 3
Antimalarial activity of pyrroloiminoquinones from the Australian marine sponge Zyzzya sp.
- Chemistry, Medicine
- Journal of medicinal chemistry
- 2012
- 47
- PDF