Disconnection analysis of CA3 and DG in mediating encoding but not retrieval in a spatial maze learning task.

@article{Jerman2006DisconnectionAO,
  title={Disconnection analysis of CA3 and DG in mediating encoding but not retrieval in a spatial maze learning task.},
  author={Taylor S Jerman and Raymond P. Kesner and Michael R Hunsaker},
  journal={Learning & memory},
  year={2006},
  volume={13 4},
  pages={458-64}
}
The dentate gyrus (DG) subregion of the hippocampus has been shown to be involved in encoding but not retrieval in a spatial maze task (modified Hebb-Williams maze). The first experiment in this study examined whether a lesion to the CA3 would contribute to a similar encoding deficit. A DG group was included in order to replicate previous results. Relative to controls, animals receiving CA3 lesions were impaired in encoding, not retrieval, on the modified Hebb-Williams maze--similar to a group… CONTINUE READING