Disclosing caffeine action on insulin sensitivity: effects on rat skeletal muscle.

@article{Sacramento2015DisclosingCA,
  title={Disclosing caffeine action on insulin sensitivity: effects on rat skeletal muscle.},
  author={J. F. Sacramento and M. Ribeiro and S. Yubero and B. Melo and A. Obeso and M. P. Guarino and C. Gonz{\'a}lez and S. Conde},
  journal={European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences},
  year={2015},
  volume={70},
  pages={
          107-16
        }
}
  • J. F. Sacramento, M. Ribeiro, +5 authors S. Conde
  • Published 2015
  • Biology, Medicine
  • European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Caffeine, a non-selective adenosine antagonist, has distinct effects on insulin sensitivity when applied acutely or chronically. Herein, we investigated the involvement of adenosine receptors on insulin resistance induced by single-dose caffeine administration. Additionally, the mechanism behind adenosine receptor-mediated caffeine effects in skeletal muscle was assessed. The effect of the administration of caffeine, 8-cycle-1,3-dipropylxanthine (DPCPX, A1 antagonist), 2-(2-Furanyl)-7-(2… Expand
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