Discharges in ventromedial frontal cortex during absence spells

@article{Tucker2007DischargesIV,
  title={Discharges in ventromedial frontal cortex during absence spells},
  author={Don M. Tucker and Micah D. Brown and Phan Dang Luu and Mark D. Holmes},
  journal={Epilepsy & Behavior},
  year={2007},
  volume={11},
  pages={546-557}
}
Neural mechanisms of conscious attention require thalamic control of widespread cortical networks. Absence spells involve a momentary loss of voluntary control of attention, during which the person is inactive and unresponsive. The spike-wave seizure discharges of these spells rapidly engage both cerebral hemispheres in the classic sign of a "generalized" seizure. Animal evidence suggests that spike-wave seizures are caused by a disruption of thalamic circuitry, with extensive spread to cortex… CONTINUE READING
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