Disappearance of thyrotropin-blocking antibodies and spontaneous recovery from hypothyroidism in autoimmune thyroiditis.

@article{Takasu1992DisappearanceOT,
  title={Disappearance of thyrotropin-blocking antibodies and spontaneous recovery from hypothyroidism in autoimmune thyroiditis.},
  author={Nobuyuki Takasu and Tetsuya Yamada and Mineyo Takasu and Ichiro Komiya and Yasuyuki Nagasawa and Takayuki Asawa and Toshio Shinoda and Toru Aizawa and Yoichi Koizumi},
  journal={The New England journal of medicine},
  year={1992},
  volume={326 8},
  pages={513-8}
}
BACKGROUND Hypothyroidism may result from the production of antibodies that block the actions of thyrotropin. How often these thyrotropin-blocking antibodies are a cause of hypothyroidism and whether their production may cease, causing hypothyroidism to disappear, have not been extensively studied. METHODS We determined the frequency with which thyrotropin-blocking antibodies were present in 172 hypothyroid patients with goitrous autoimmune thyroiditis (Hashimoto's disease) and 64 hypothyroid… CONTINUE READING
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