Disaggregation of amphotericin B by sodium deoxycholate micellar aggregates.

@article{Selvam2008DisaggregationOA,
  title={Disaggregation of amphotericin B by sodium deoxycholate micellar aggregates.},
  author={Susithra Selvam and Ashok Kumar Mishra},
  journal={Journal of photochemistry and photobiology. B, Biology},
  year={2008},
  volume={93 2},
  pages={66-70}
}
Amphotericin B (AmB) is present as aggregates in aqueous media. Sodium deoxycholate (NaDC) is known to cause disaggregation of AmB and to form monomers, as is observed by the increase of absorbance at 414 nm. By following the fluorescence intensity at 472 nm (lambda(ex) 335 nm), it was found that with increasing NaDC concentration there is a progressive… CONTINUE READING