Disability progression in a clinical trial of relapsing-remitting multiple sclerosis: eight-year follow-up.

@article{Rudick2010DisabilityPI,
  title={Disability progression in a clinical trial of relapsing-remitting multiple sclerosis: eight-year follow-up.},
  author={Richard A. Rudick and Jar-Chi Lee and Gary R. Cutter and Deborah M. Miller and Dennis N. Bourdette and Bianca Weinstock-Guttman and Robert Hyde and Hao Zhang and Xiaojun You},
  journal={Archives of neurology},
  year={2010},
  volume={67 11},
  pages={1329-35}
}
OBJECTIVE To investigate the value of Expanded Disability Status Scale (EDSS) worsening sustained for at least 6 months and other parameters as predictors for disability status. DESIGN Retrospective analysis of the Multiple Sclerosis Collaborative Research Group study data. SETTING The intramuscular interferon beta-1a pivotal trial was a double-blind, placebo-controlled phase 3 study. PARTICIPANTS Patients with relapsing-remitting multiple sclerosis who received at least 2 years of… CONTINUE READING

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