Disability and T2 MRI lesions: a 20-year follow-up of patients with relapse onset of multiple sclerosis.

  title={Disability and T2 MRI lesions: a 20-year follow-up of patients with relapse onset of multiple sclerosis.},
  author={L. Fisniku and P. Brex and D. Altmann and K. A. Miszkiel and C. E. Benton and R. Lanyon and A. Thompson and D. Miller},
  journal={Brain : a journal of neurology},
  volume={131 Pt 3},
  • L. Fisniku, P. Brex, +5 authors D. Miller
  • Published 2008
  • Medicine
  • Brain : a journal of neurology
  • Clinically isolated syndromes (CIS), such as optic neuritis, brainstem or spinal cord syndromes are frequently the first clinical presentations of multiple sclerosis. However, not all CIS patients develop multiple sclerosis and in those who do, disability is highly variable. In previous follow-up studies, brain lesions on T2-weighted MRI are associated with increased risk of multiple sclerosis and to an extent disability. We evaluated the longitudinal relationships between the MRI lesions and… CONTINUE READING
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