Dirty-appearing white matter in multiple sclerosis

  title={Dirty-appearing white matter in multiple sclerosis},
  author={FRCPC G. R. W. Moore and Cornelia Laule and Alex MacKay and E. Leung M.Sc and FRCPC D. K. B. Li and Guo-jun Zhao and FRCPC A. L. Traboulsee and FRCPC D. W. Paty},
  journal={Journal of Neurology},
“Dirty-appearing white matter” (DAWM) in multiple sclerosis (MS) is defined as a region(s) with ill-defined borders of intermediate signal intensity between that of normal-appearing white matter (NAWM) and that of plaque on T2-weighted and proton density imaging. To delineate the histopathology of DAWM, four formalin-fixed cerebral hemisphere slices of three MS patients with DAWM were scanned with T2- weighted and proton density sequences. The myelin water fraction (MWF) was obtained by… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 28 extracted citations


Publications referenced by this paper.
Showing 1-10 of 61 references

MRI dirty-appearing white matter in MS. (Abstract)

  • GJ Zhao, DKB Li, Y Cheng, XY Wang, DW Paty
  • Neurology 54(Suppl
  • 2000
Highly Influential
4 Excerpts

Dirty - appearing white matter in multiple sclerosis : relationship to T 2 disease burden increase and brain volume decrease with 8 - year long - term follow - up ( abstract )

  • VT MiropoloskyV, G Zhao, Y Zhao, A Traboulsee, Li DKB
  • Mult Scler
  • 2006

Pathology of the normal-appearing white matter in multiple sclerosis

  • W Bruck, C Stadelmann
  • 2004
1 Excerpt

Similar Papers

Loading similar papers…