Dirty-appearing white matter in multiple sclerosis

@article{Moore2008DirtyappearingWM,
  title={Dirty-appearing white matter in multiple sclerosis},
  author={FRCPC G. R. W. Moore and Cornelia Laule and Alex MacKay and E. Leung M.Sc and FRCPC D. K. B. Li and Guo-jun Zhao and FRCPC A. L. Traboulsee and FRCPC D. W. Paty},
  journal={Journal of Neurology},
  year={2008},
  volume={255},
  pages={1802-1811}
}
“Dirty-appearing white matter” (DAWM) in multiple sclerosis (MS) is defined as a region(s) with ill-defined borders of intermediate signal intensity between that of normal-appearing white matter (NAWM) and that of plaque on T2-weighted and proton density imaging. To delineate the histopathology of DAWM, four formalin-fixed cerebral hemisphere slices of three MS patients with DAWM were scanned with T2- weighted and proton density sequences. The myelin water fraction (MWF) was obtained by… CONTINUE READING

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