Dirigent proteins: molecular characteristics and potential biotechnological applications

  title={Dirigent proteins: molecular characteristics and potential biotechnological applications},
  author={B. Pickel and A. Schaller},
  journal={Applied Microbiology and Biotechnology},
  • B. Pickel, A. Schaller
  • Published 2013
  • Chemistry, Medicine
  • Applied Microbiology and Biotechnology
  • Dirigent proteins (DIRs) are thought to play important roles in plant secondary metabolism. They lack catalytic activity but direct the outcome of bimolecular coupling reactions toward regio- and stereospecific product formation. Functionally described DIRs confer specificity to the oxidative coupling of coniferyl alcohol resulting in the preferred production of either (+)- or (−)-pinoresinol, which are the first intermediates in the enantiocomplementary pathways for lignan biosynthesis. DIRs… CONTINUE READING
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