Directionality of fission yeast mating-type interconversion is controlled by the location of the donor loci.

@article{Thon1993DirectionalityOF,
  title={Directionality of fission yeast mating-type interconversion is controlled by the location of the donor loci.},
  author={Genevi{\`e}ve Thon and Amar J. S. Klar},
  journal={Genetics},
  year={1993},
  volume={134 4},
  pages={1045-54}
}
Cells of homothallic strains of Schizosaccharomyces pombe efficiently switch between two mating types called P and M. The phenotypic switches are due to conversion of the expressed mating-type locus (mat1) by two closely linked silent loci, mat2-P and mat3-M, that contain unexpressed information for the P and M mating types, respectively. In this process, switching-competent cells switch to the opposite mating type in 72-90% of the cell divisions. Hence, mat2-P is a preferred donor of… CONTINUE READING