Directional selection and variation in finite populations.

@article{Keightley1987DirectionalSA,
  title={Directional selection and variation in finite populations.},
  author={Peter D. Keightley and W G Hill},
  journal={Genetics},
  year={1987},
  volume={117 3},
  pages={573-82}
}
Predictions are made of the equilibrium genetic variances and responses in a metric trait under the joint effects of directional selection, mutation and linkage in a finite population. The "infinitesimal model" is analyzed as the limiting case of many mutants of very small effect, otherwise Monte Carlo simulation is used. If the effects of mutant genes on the trait are symmetrically distributed and they are unlinked, the variance of mutant effects is not an important parameter. If the… CONTINUE READING
23 Citations
5 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-5 of 5 references

The combination of linkage values and the calculation of distance between loci of linked factors

  • R. W. HAMMING
  • J . Genet .
  • 1919

The correlation between relatives on the supposition of Mendelian inheritance

  • J. B. S. HALDANE
  • 1918

a Rates of change in quantitative traits from fixation of new mutations

  • W. G. HILL
  • Proc . Natl . Acad . Sci . USA

Similar Papers

Loading similar papers…