Directional secretion and transport of leptin and expression of leptin receptor isoforms in human placental BeWo cells.

Abstract

Placental leptin secretion has important implications for maternal adaptation to pregnancy, fetal growth and development, and local autocrine/paracrine actions within trophoblast. In this study we used a cell culture insert model to examine directional secretion of leptin from the basal and apical surfaces of human choriocarcinoma BeWo cells, and to assess… (More)

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