Directional neurite growth using carbon nanotube patterned substrates as a biomimetic cue.

@article{Jang2010DirectionalNG,
  title={Directional neurite growth using carbon nanotube patterned substrates as a biomimetic cue.},
  author={Min Jee Jang and Seon Namgung and Seunghun Hong and Yoonkey Nam},
  journal={Nanotechnology},
  year={2010},
  volume={21 23},
  pages={235102}
}
Researchers have made extensive efforts to mimic or reverse-engineer in vivo neural circuits using micropatterning technology. Various surface chemical cues or topographical structures have been proposed to design neuronal networks in vitro. In this paper, we propose a carbon nanotube (CNT)-based network engineering method which naturally mimics the structure of extracellular matrix (ECM). On CNT patterned substrates, poly-L-lysine (PLL) was coated, and E18 rat hippocampal neurons were cultured… CONTINUE READING