Directed reduction of beta-amino ketones to syn or anti 1,3-amino alcohol derivatives.

@article{Keck2002DirectedRO,
  title={Directed reduction of beta-amino ketones to syn or anti 1,3-amino alcohol derivatives.},
  author={Gary E. Keck and Anh P Truong},
  journal={Organic letters},
  year={2002},
  volume={4 18},
  pages={3131-4}
}
[reaction: see text] The reduction of beta-amino ketones with samarium(II) iodide has been investigated. Either the syn or anti 1,3-amino alcohols can be obtained as the major product due to a divergence in selectivity with different N-protecting groups.